Visible-Light-Promoted Continuous-Flow Iodination of Primary C(sp <sup>3</sup> )–H Bonds: An Undirected and Regioselective Approach
)-H functionalization. Mechanistic investigations indicate that the reaction proceeds through a reversible and nonselective C-H activation to generate a mixture of alkyl radicals, followed by a kinetically controlled iodination that selectively traps the primary radical species.
Authors
- S M Li
- Jinglian Nong
- Y T Wang
- Dandan Yuan
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/jacs.6c02161
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China