Bacterial-Derived C6-HSL Regulates Lignin Synthesis and Enhances Disease Resistance in Apple ( <i>Malus domestica</i> ) by Targeting and Degrading MdWRKY22
. DNA affinity purification sequencing (DAP-seq) and luciferase (LUC) assay revealed that MdWRKY22 binds to the promoter of apple mannitol dehydrogenase (MdMTD) and activates its transcription. The apple transient transformation experiment indicates that MdMTD has a negative regulatory effect on lignin biosynthesis and disease resistance. Collectively, C6-HSL reduces the transcription of MdMTD by degrading MdWRKY22, thereby enhancing the accumulation of lignin and disease resistance in apple.
Authors
- Ling Sun (ORCID: https://orcid.org/0000-0002-4361-9538)
- Ruolin Wang (ORCID: https://orcid.org/0000-0003-0716-5206)
- Tiecheng Shi
- Shang Liu (ORCID: https://orcid.org/0000-0001-6318-3746)
- Yan Xia (ORCID: https://orcid.org/0000-0002-4114-7282)
- Lili Huang (ORCID: https://orcid.org/0000-0002-3638-9789)
Institutions
- Institute of Plant Protection (CN)
- Life University (US)
- Northwest A&F University (CN)
Publication Details
- Journal
- Journal of Agricultural and Food Chemistry
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.jafc.5c15952
- Primary Topic
- Plant Gene Expression Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China National Tobacco Corporation