An <i>o</i> -Nitroveratryloxycarbonyl-Based Photolabile Solubilizing Tag for the Chemical Synthesis of Poorly Soluble Peptides and Proteins
UV irradiation. This strategy facilitates efficient handling of challenging fragments and supports downstream peptide ligation for the synthesis of hydrophobic proteins.
Authors
- Yoshiki Shimizu (ORCID: https://orcid.org/0000-0002-2991-1356)
- Tetsuo Narumi (ORCID: https://orcid.org/0000-0003-2412-4035)
- Nobuyuki Mase (ORCID: https://orcid.org/0000-0001-6244-4916)
- Kohei Sato (ORCID: https://orcid.org/0000-0001-6877-9223)
- Yoshinori Taguchi
- Taiyo Hagiwara
Institutions
- Shizuoka University (JP)
- Biochemical Society (GB)
- Photonics (United States) (US)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.orglett.6c01311
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Support for Pioneering Research Initiated by the Next Generation
- Naito Foundation
- Takeda Science Foundation
- Japan Society for the Promotion of Science