GE11/RGD Dual-Ligand Copper Nanoassemblies Synchronize Cuproptosis and Photothermal Therapy for Targeted Cervical Cancer Ablation
, tumor temperature ∼ 51 °C) achieves potent and long-lasting tumor suppression for 21 days, without obvious body weight loss or histological damage to major organs. By integrating dual-ligand targeting with synergistic cuproptosis and photothermal therapy, this study provides an effective, low-toxicity, and precise strategy for cervical cancer treatment.
Authors
- Xiaobin Guo (ORCID: https://orcid.org/0000-0003-1708-838X)
- Yonghai Feng (ORCID: https://orcid.org/0000-0001-5794-5871)
- Lu Liu (ORCID: https://orcid.org/0000-0001-7464-2776)
- Xiaoya Xu (ORCID: https://orcid.org/0000-0002-2764-256X)
- Rong Li (ORCID: https://orcid.org/0000-0003-2608-9325)
- Shiyun Xue
- Z Y Chen
- Zhiyi Wei
- Chang Gao
- Lin Tang
- Nan Yang
- Tianyuan Su
- Zuoling Yang
- Lu Ding
- Jiaming Du
Institutions
- Jiangsu University (CN)
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Sixth Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Molecular Pharmaceutics
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.molpharmaceut.6c00002
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00