Enhanced Risk Stratification of Atrial Fibrillation Detected After Ischemic Stroke and <scp>TIA</scp> : The Role of Apnoea–Hypopnoea Index and Hypoxic Burden—A Study From the Bern Sleep‐Stroke Registry

). Logistic regression adjusted for age, sex, and cardiovascular risk factors assessed associations between apnoea-hypopnoea index/hypoxic burden categories and atrial fibrillation. Among 911 patients (mean age 66 ± 14 years, 62% male), atrial fibrillation was detected in 145 (16%) patients. Patients with both apnoea-hypopnoea index ≥ 15 and high hypoxic burden had nearly double the odds of atrial fibrillation compared to those with low apnoea-hypopnoea index and low hypoxic burden (adjusted odds ratio 1.97, 95% CI 1.25-3.12). In contrast, neither elevated apnoea-hypopnoea index nor high hypoxic burden alone demonstrated a statistically significant association. Elevated apnoea-hypopnoea index combined with high hypoxic burden identifies stroke patients at higher risk of atrial fibrillation. Integrating these metrics into post-stroke evaluation may improve personalized management and secondary prevention of recurrent cardiovascular or cerebrovascular events.