Validation of the <scp>TruBlue</scp> Light Laser for Laryngeal Somatosensory and Perturbation Testing

OBJECTIVES: Clinical assessment of laryngeal somatosensation is limited by the lack of precise tools to directly stimulate the larynx and quantify sensorimotor responses. This study validated a blue light laser method for laryngeal somatosensory testing in vocally healthy adults and developed acoustic measures to quantify vocal responses to controlled laryngeal perturbations. METHODS: In this prospective validation study, a 445-nm diode blue light laser was delivered through a channeled flexible laryngoscope to the arytenoid mucosa. Single subablative pulses (1-10 W, 30 ms) were applied during quiet breathing or sustained phonation to determine perceptual and reflexive sensory thresholds, discrimination acuity, and laryngeal perturbation responses. Acoustic recordings during perturbations were analyzed in Praat using custom software to extract continuous fundamental frequency variability and quantify perturbation magnitude and recovery. RESULTS: ) = 19.35 Hz; recovery = 0.48 s). CONCLUSION: Blue light laser stimulation is a feasible and precise method for evaluating laryngeal somatosensation and vocal sensorimotor responses.

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Publication Details

Journal
The Laryngoscope
Published
2026-04-25
DOI
https://doi.org/10.1002/lary.70585
Primary Topic
Voice and Speech Disorders
Type
article
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article

Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing

Adrianna C. Shembel, Lesley F. Childs, Shumon I. Dhar, Ted Mau et al.
The Laryngoscope
Voice and Speech Disorders
article

Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing

Adrianna C. Shembel, Lesley F. Childs, Shumon I. Dhar, Ted Mau, Youri Maryn, Elizabeth Young, Julianna Smeltzer
article en

Abstract

OBJECTIVES: Clinical assessment of laryngeal somatosensation is limited by the lack of precise tools to directly stimulate the larynx and quantify sensorimotor responses. This study validated a blue light laser method for laryngeal somatosensory testing in vocally healthy adults and developed acoustic measures to quantify vocal responses to controlled laryngeal perturbations. METHODS: In this prospective validation study, a 445-nm diode blue light laser was delivered through a channeled flexible laryngoscope to the arytenoid mucosa. Single subablative pulses (1-10 W, 30 ms) were applied during quiet breathing or sustained phonation to determine perceptual and reflexive sensory thresholds, discrimination acuity, and laryngeal perturbation responses. Acoustic recordings during perturbations were analyzed in Praat using custom software to extract continuous fundamental frequency variability and quantify perturbation magnitude and recovery. RESULTS: ) = 19.35 Hz; recovery = 0.48 s). CONCLUSION: Blue light laser stimulation is a feasible and precise method for evaluating laryngeal somatosensation and vocal sensorimotor responses.

The Laryngoscope
The University of Texas at Dallas (US), Palo Alto University (US), European Institute for Advanced Studies in Management (BE), Ghent University (BE), Province of Antwerp (BE), The University of Texas Southwestern Medical Center (US)
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Voice and Speech Disorders
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