Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single‐Center Cohort Study

BACKGROUND: ) exposure and postoperative complications, highlighting its interpretability and flexibility for clinical environmental epidemiology. METHODS: concentrations in the 7 days prior to surgery. The binary outcome was a composite of postoperative complications: pneumonia, surgical site infection, urinary tract infection, sepsis, stroke, myocardial infarction, or thromboembolic event. A hierarchical Bayesians regression model with weakly informative priors was used adjusting for age, sex, season, neighborhood disadvantage, and the Elixhauser index of comorbidities with census tract as a group (random) effect. We present posterior estimates with credible intervals, highlight model transparency and sensitivity, and discuss contrasts with standard frequentist methods. RESULTS: , the odds of complication rose to over 27% (95% CI: 4%-55%). The results were robust across prior choices and model specifications. We report full posterior distributions and highlight advantages of Bayesian modeling for uncertainty quantification and clinical interpretability. CONCLUSIONS: exposure and postoperative complications, highlighting transparent risk estimation and uncertainty characterization that may inform the design of future multicenter perioperative environmental studies. EDITORIAL COMMENT: Using Bayesian statistical analysis, the authors demonstrate a dose-dependent risk for postoperative complications in patients exposed to air polluted with fine particulate matter with a size of less than 2.5 μm.

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Publication Details

Journal
Acta Anaesthesiologica Scandinavica
Published
2026-04-26
DOI
https://doi.org/10.1111/aas.70235
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
0.00

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article

Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single‐Center Cohort Study

Cameron K. Jacobson, Neng Wan, Nathan L. Pace, Tabitha M. Benney et al.
Acta Anaesthesiologica Scandinavica
Air Quality and Health Impacts
article

Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single‐Center Cohort Study

Cameron K. Jacobson, Neng Wan, Nathan L. Pace, Tabitha M. Benney, John F. Pearson, Matthew J. Strickland, Calvin S. Riss, Cade K. Kartchner, Longyin Lee, Jacob A. Wood, Ben K. Goodrich, Jonah S. Gabry, Michael H. Andreae, John V. Pham
article en

Abstract

BACKGROUND: ) exposure and postoperative complications, highlighting its interpretability and flexibility for clinical environmental epidemiology. METHODS: concentrations in the 7 days prior to surgery. The binary outcome was a composite of postoperative complications: pneumonia, surgical site infection, urinary tract infection, sepsis, stroke, myocardial infarction, or thromboembolic event. A hierarchical Bayesians regression model with weakly informative priors was used adjusting for age, sex, season, neighborhood disadvantage, and the Elixhauser index of comorbidities with census tract as a group (random) effect. We present posterior estimates with credible intervals, highlight model transparency and sensitivity, and discuss contrasts with standard frequentist methods. RESULTS: , the odds of complication rose to over 27% (95% CI: 4%-55%). The results were robust across prior choices and model specifications. We report full posterior distributions and highlight advantages of Bayesian modeling for uncertainty quantification and clinical interpretability. CONCLUSIONS: exposure and postoperative complications, highlighting transparent risk estimation and uncertainty characterization that may inform the design of future multicenter perioperative environmental studies. EDITORIAL COMMENT: Using Bayesian statistical analysis, the authors demonstrate a dose-dependent risk for postoperative complications in patients exposed to air polluted with fine particulate matter with a size of less than 2.5 μm.

Acta Anaesthesiologica ScandinavicaVol. 70(6)
University of Nevada, Reno (US), City University of New York (US), University of Utah (US), Columbia University Irving Medical Center (US), Sustainability Institute (ZA), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), Columbia University (US), Stanford University (US)
National Science Foundation, National Cancer Institute, National Institute of Environmental Health Sciences
Openalex Percentile: Top 12%
Air Quality and Health Impacts
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