Is Motion Preservation With Three-Level Hybrid Cervical Surgery Achieved Without Compromising Clinical Outcomes? A Systematic Review and Meta-Analysis
= 0.93) comparable to ACDF. Fusion rates at intended arthrodesis levels were high and similar in both cohorts. There were no significant differences in total, early or late complication rates, although heterogeneity was moderate to high across several outcomes.ConclusionIn three-level cervical degenerative disease, hybrid surgery and ACDF provide equivalent improvements in pain, disability, neurological recovery, alignment, fusion success, and complication profiles. Hybrid constructs demonstrated a trend towards greater preservation cervical range of motion without compromising clinical efficacy or safety. These findings support hybrid surgery as a selective, motion-preserving alternative to three-level ACDF in appropriately chosen patients.Level of evidenceII.
Authors
- Khan Sharun (ORCID: https://orcid.org/0000-0003-1040-3746)
- Sathish Muthu (ORCID: https://orcid.org/0000-0002-7143-4354)
- Sakthivel Rajan Rajaram Manoharan (ORCID: https://orcid.org/0000-0002-4772-2911)
- Satish Kumar Rajappan Chandra
- Vibhu Krishnan Viswanathan (ORCID: https://orcid.org/0000-0002-3804-1698)
- Dhibin Vikash Kolarpatti Ponnusamy
- Steven Theiss
- Vaishnavi Sampathkumar
Institutions
- SRM Institute of Science and Technology (IN)
- University of Alabama (US)
- Vinayaka Missions University (IN)
- Columbia Orthopaedic Group (US)
- Vivekananda Institute of Medical Sciences (IN)
- Yuan Ze University (TW)
Publication Details
- Journal
- Global Spine Journal
- Published
- 2026-04-26
- DOI
- https://doi.org/10.1177/21925682261447886
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 0.00