Is Motion Preservation With Three-Level Hybrid Cervical Surgery Achieved Without Compromising Clinical Outcomes? A Systematic Review and Meta-Analysis

= 0.93) comparable to ACDF. Fusion rates at intended arthrodesis levels were high and similar in both cohorts. There were no significant differences in total, early or late complication rates, although heterogeneity was moderate to high across several outcomes.ConclusionIn three-level cervical degenerative disease, hybrid surgery and ACDF provide equivalent improvements in pain, disability, neurological recovery, alignment, fusion success, and complication profiles. Hybrid constructs demonstrated a trend towards greater preservation cervical range of motion without compromising clinical efficacy or safety. These findings support hybrid surgery as a selective, motion-preserving alternative to three-level ACDF in appropriately chosen patients.Level of evidenceII.

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Publication Details

Journal
Global Spine Journal
Published
2026-04-26
DOI
https://doi.org/10.1177/21925682261447886
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
Field-Weighted Citation Impact
0.00
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article

Is Motion Preservation With Three-Level Hybrid Cervical Surgery Achieved Without Compromising Clinical Outcomes? A Systematic Review and Meta-Analysis

Khan Sharun, Sathish Muthu, Sakthivel Rajan Rajaram Manoharan, Satish Kumar Rajappan Chandra et al.
Global Spine Journal
Cervical and Thoracic Myelopathy
article

Is Motion Preservation With Three-Level Hybrid Cervical Surgery Achieved Without Compromising Clinical Outcomes? A Systematic Review and Meta-Analysis

Khan Sharun, Sathish Muthu, Sakthivel Rajan Rajaram Manoharan, Satish Kumar Rajappan Chandra, Vibhu Krishnan Viswanathan, Dhibin Vikash Kolarpatti Ponnusamy, Steven Theiss, Vaishnavi Sampathkumar
article en

Abstract

= 0.93) comparable to ACDF. Fusion rates at intended arthrodesis levels were high and similar in both cohorts. There were no significant differences in total, early or late complication rates, although heterogeneity was moderate to high across several outcomes.ConclusionIn three-level cervical degenerative disease, hybrid surgery and ACDF provide equivalent improvements in pain, disability, neurological recovery, alignment, fusion success, and complication profiles. Hybrid constructs demonstrated a trend towards greater preservation cervical range of motion without compromising clinical efficacy or safety. These findings support hybrid surgery as a selective, motion-preserving alternative to three-level ACDF in appropriately chosen patients.Level of evidenceII.

Global Spine Journal
SRM Institute of Science and Technology (IN), University of Alabama (US), Vinayaka Missions University (IN), Columbia Orthopaedic Group (US), Vivekananda Institute of Medical Sciences (IN), Yuan Ze University (TW)
Reduced inequalities
Openalex Percentile: Top 6%
Cervical and Thoracic Myelopathy
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