Design, construction and validation of an open-source gold nanoparticle concentration tracking device

Gold nanoparticles (GNPs) exhibit unique optical properties governed by localized surface plasmon resonance, enabling applications in biomedicine, sensing, catalysis, and photonics. Accurate concentration tracking during fabrication is essential, since particle density strongly affects colloid stability and functional performance. Pulsed laser ablation in liquids (PLAL) has gained recognition as a sustainable route for nanoparticle synthesis, ligand-free, high-purity colloids without chemical by-products. However, monitoring GNP concentration during PLAL typically relies on UV-VIS spectrophotometers, that can be costly, bulky, and difficult to integrate into fabrication workflows. In this work, we present the design, construction, and validation of a compact, open-source alternative for real-time nanoparticle tracking. The device combines a 405 nm laser, a photodiode, and an ESP32-S3 microcontroller for data-acquisition and processing. All design files, firmware, and 3D-printed casing are openly released. Validation experiments show strong agreement with conventional UV-VIS absorption, demonstrating that the proposed device can replace commercial spectrophotometers. By providing a concentration sensor that can be easily integrated in a production chain, this approach reduces the physical footprint and cost of GNPs fabrication facilities, while maintaining reliable monitoring. With a cost below 40 € and modular architecture, the system enables reproducible, accessible, and sustainable monitoring for PLAL and other nanomaterial synthesis processes.

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Publication Details

Journal
HardwareX
Published
2026-04-26
DOI
https://doi.org/10.1016/j.ohx.2026.e00778
Primary Topic
Gold and Silver Nanoparticles Synthesis and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Design, construction and validation of an open-source gold nanoparticle concentration tracking device

Gladys Mı́nguez-Vega, Carlos Doñate-Buendía, Vicent Sorribes-Paulo, Lucía Arrufat-Sorli et al.
HardwareX
Gold and Silver Nanoparticles Synthesis and Applications
article

Design, construction and validation of an open-source gold nanoparticle concentration tracking device

Gladys Mı́nguez-Vega, Carlos Doñate-Buendía, Vicent Sorribes-Paulo, Lucía Arrufat-Sorli, Heberley Tobón-Maya, Francis Rey-Cortes, Sergio Molina-Prados
article en

Abstract

Gold nanoparticles (GNPs) exhibit unique optical properties governed by localized surface plasmon resonance, enabling applications in biomedicine, sensing, catalysis, and photonics. Accurate concentration tracking during fabrication is essential, since particle density strongly affects colloid stability and functional performance. Pulsed laser ablation in liquids (PLAL) has gained recognition as a sustainable route for nanoparticle synthesis, ligand-free, high-purity colloids without chemical by-products. However, monitoring GNP concentration during PLAL typically relies on UV-VIS spectrophotometers, that can be costly, bulky, and difficult to integrate into fabrication workflows. In this work, we present the design, construction, and validation of a compact, open-source alternative for real-time nanoparticle tracking. The device combines a 405 nm laser, a photodiode, and an ESP32-S3 microcontroller for data-acquisition and processing. All design files, firmware, and 3D-printed casing are openly released. Validation experiments show strong agreement with conventional UV-VIS absorption, demonstrating that the proposed device can replace commercial spectrophotometers. By providing a concentration sensor that can be easily integrated in a production chain, this approach reduces the physical footprint and cost of GNPs fabrication facilities, while maintaining reliable monitoring. With a cost below 40 € and modular architecture, the system enables reproducible, accessible, and sustainable monitoring for PLAL and other nanomaterial synthesis processes.

HardwareXVol. 26
Universitat Jaume I (ES)
Generalitat Valenciana, Universitat Jaume I
Industry, innovation and infrastructure
Openalex Percentile: Top 21%
Gold and Silver Nanoparticles Synthesis and Applications
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