A <i>pcyt-1</i> Allelic Series Reveals In Vivo Consequences of Reduced Phosphatidylcholine Synthesis in <i>C. elegans</i>
allelic series and show that limiting PC synthesis drives compensatory remodeling toward LCPUFA-enriched membranes while rendering the germline particularly vulnerable.
Authors
- Marcus Henricsson (ORCID: https://orcid.org/0000-0002-4202-0339)
- Jan Borén (ORCID: https://orcid.org/0000-0003-0786-8091)
- Delaney Kaper (ORCID: https://orcid.org/0000-0002-9929-8104)
- Marc Pilon (ORCID: https://orcid.org/0000-0003-3919-2882)
- August Qvist (ORCID: https://orcid.org/0009-0005-9566-9026)
- Albin Stjernman
Institutions
- Wallenberg Wood Science Center (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-26
- DOI
- https://doi.org/10.64898/2026.04.22.720214
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00