Antioxidant, antimicrobial, and apoptosis-related activities of Azadirachta indica (Neem) leaf extract in MCF-7 and A549 cell lines
of 128.1 and 55.7 µg/ml for A549 and MCF-7, respectively. The extract promotes arrest of cell cycle at G0, inhibited the anti-apoptotic genes and stimulated the pro-apoptotic ones. In conclusion, neem leaves extract could have promising roles in pharmaceutical and medical applications.
Authors
- Sami Rabei (ORCID: https://orcid.org/0000-0001-6042-5877)
- mohammed marzouk
- Rasha F. Zahran (ORCID: https://orcid.org/0000-0001-9530-1751)
- Elshahat A. Toson
- Norhan A. Rezk
Institutions
- Damietta University (EG)
Publication Details
- Journal
- Scientific Reports
- Published
- 2026-04-26
- DOI
- https://doi.org/10.1038/s41598-026-48147-5
- Primary Topic
- Insect Pest Control Strategies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Development Fund