Multi-omic phenotyping of MAPT V337M neurons reveals early changes in axonogenesis and tau phosphorylation

Authors

Andrea Keys
Andrew Li
Justin McKetney (ORCID: https://orcid.org/0000-0002-2405-8288)
Gary Dixon (ORCID: https://orcid.org/0000-0002-6616-4740)
Steven Boggess (ORCID: https://orcid.org/0000-0001-9232-4122)
Avi J. Samelson
Gregory Mohl (ORCID: https://orcid.org/0000-0002-8036-7886)
Danielle L. Swaney (ORCID: https://orcid.org/0000-0001-6119-6084)
Carlota Pereda Serras
Emily Marzette
Julianne Jin (ORCID: https://orcid.org/0009-0008-9877-9716)
Cristian Chavira
Nabeela Ariqat
Martin Kampmann

Institutions

QB3 (US)
Gladstone Institutes (US)
University of California, San Francisco (US)
Quantitative BioSciences (US)
Institute for Neurodegenerative Disorders (US)

Publication Details

Journal: npj Dementia
Published: 2026-04-25
DOI: https://doi.org/10.1038/s44400-026-00076-w
Primary Topic: Alzheimer's disease research and treatments
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Alzheimer's Association
Chan Zuckerberg Initiative
Rainwater Charitable Foundation
National Institute on Aging
National Institute of Neurological Disorders and Stroke

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article

Multi-omic phenotyping of MAPT V337M neurons reveals early changes in axonogenesis and tau phosphorylation

Andrea Keys, Andrew Li, Justin McKetney, Gary Dixon et al.

Apr 25, 2026

npj Dementia

Alzheimer's disease research and treatments

article

Multi-omic phenotyping of MAPT V337M neurons reveals early changes in axonogenesis and tau phosphorylation

Andrea Keys, Andrew Li, Justin McKetney, Gary Dixon, Steven Boggess, Avi J. Samelson, Gregory Mohl, Danielle L. Swaney, Carlota Pereda Serras, Emily Marzette, Julianne Jin, Cristian Chavira, Nabeela Ariqat, Martin Kampmann

April 25, 2026article en

Abstract

No abstract available for this paper.

npj DementiaVol. 2(1)

QB3 (US), Gladstone Institutes (US), University of California, San Francisco (US), Quantitative BioSciences (US), Institute for Neurodegenerative Disorders (US)

Alzheimer's Association, Chan Zuckerberg Initiative, Rainwater Charitable Foundation, National Institute on Aging, National Institute of Neurological Disorders and Stroke

Good health and well-being

Openalex Percentile: Top 8%

Alzheimer's disease research and treatments

DOI Open Access PDF OpenAlex

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