Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice

depend on CREB activation (phosphorylation). These findings suggest that stress-induced elevations in D1R-associated DYN signaling within the NAc is a biomarker of susceptibility.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-24
DOI
https://doi.org/10.64898/2026.04.23.720476
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
0.00
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article

Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice

William A. Carlezon, Dominika J. Burek
bioRxiv (Cold Spring Harbor Laboratory)
Neurotransmitter Receptor Influence on Behavior
article

Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice

William A. Carlezon, Dominika J. Burek
article en

Abstract

depend on CREB activation (phosphorylation). These findings suggest that stress-induced elevations in D1R-associated DYN signaling within the NAc is a biomarker of susceptibility.

bioRxiv (Cold Spring Harbor Laboratory)
Harvard University (US), McLean Hospital (US)
Reduced inequalities
Openalex Percentile: Top 12%
Neurotransmitter Receptor Influence on Behavior
DOIOpen Access PDFOpenAlex
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Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice — William A. Carlezon, Dominika J. Burek · bioRxiv (Cold Spring Harbor Laboratory) (2026) | TGRS Research Map | TGRS