Green Tea Consumption Potentiates Paclitaxel Cytotoxic Efficacy in Vitro and Antitumor Efficacy in Vivo: A Pharmacodynamic and Pharmacokinetic Study
of paclitaxel and a 28.29% increase in the AUC. Moreover, long-term green tea consumption significantly reduced hepatic microsomal protein level. Taken together, green tea consumption enhances the anticancer efficacy and increases the pharmacokinetic profile of paclitaxel, which provides information to study the interaction between herbs and chemotherapy.
Authors
- Y P Zhang
- Shuai Lü (ORCID: https://orcid.org/0000-0001-6171-5032)
- Qiaoling Chen (ORCID: https://orcid.org/0000-0001-8913-3077)
- Yingqian Ci
- Huajun Li (ORCID: https://orcid.org/0000-0003-4455-6193)
- Jinping Qiao (ORCID: https://orcid.org/0000-0001-9297-7561)
- Yue Wang (ORCID: https://orcid.org/0000-0003-0098-5359)
- Mei Han (ORCID: https://orcid.org/0000-0003-3834-6667)
- Na Du (ORCID: https://orcid.org/0000-0003-2455-3497)
- Xu S
- Feifei Chen
- Chang Qing
Institutions
- Beijing Normal University (CN)
Publication Details
- Journal
- Phytotherapy Research
- Published
- 2026-04-24
- DOI
- https://doi.org/10.1002/ptr.70207
- Primary Topic
- Tea Polyphenols and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00