Front Cover: Copper‐Catalyzed Sequential Azide‐Alkyne Cycloaddition (CuAAc) and Ullmann Coupling: A Tandem One‐Pot Synthesis of Quinazolino[3,2‐ <i>c</i> ][1,2,3] Triazolo[1,5‐ <i>a</i> ]‐Quinazolin‐14‐One (Eur. J. Org. Chem. 15/2026)
The Front Cover shows a copper-catalyzed tandem strategy that enables the efficient synthesis of triazole-fused quinazolinones through a multicomponent reaction of 2-bromophenyl quinazolinones, sodium azide, and terminal alkynes. Integrating CuAAC and Ulmann-type C–N coupling under mild, ligand-free conditions, this method yields diverse polycyclic N-heterocycles with broad substrate scope. More information can be found in the Research Article by M. Alla and co-workers (DOI: 10.1002/ejoc.202501064).
Authors
- Gal Reddy Potuganti (ORCID: https://orcid.org/0000-0002-1390-9526)
- Manjula Alla (ORCID: https://orcid.org/0000-0001-6010-8767)
- Aravind Kandula
- Shreya Patlolla
Institutions
- Indian Institute of Chemical Technology (IN)
- University of Oklahoma (US)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1002/ejoc.70471
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00