Front Cover: Copper‐Catalyzed Sequential Azide‐Alkyne Cycloaddition (CuAAc) and Ullmann Coupling: A Tandem One‐Pot Synthesis of Quinazolino[3,2‐ <i>c</i> ][1,2,3] Triazolo[1,5‐ <i>a</i> ]‐Quinazolin‐14‐One (Eur. J. Org. Chem. 15/2026)

The Front Cover shows a copper-catalyzed tandem strategy that enables the efficient synthesis of triazole-fused quinazolinones through a multicomponent reaction of 2-bromophenyl quinazolinones, sodium azide, and terminal alkynes. Integrating CuAAC and Ulmann-type C–N coupling under mild, ligand-free conditions, this method yields diverse polycyclic N-heterocycles with broad substrate scope. More information can be found in the Research Article by M. Alla and co-workers (DOI: 10.1002/ejoc.202501064).

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Publication Details

Journal
European Journal of Organic Chemistry
Published
2026-04-22
DOI
https://doi.org/10.1002/ejoc.70471
Primary Topic
Quinazolinone synthesis and applications
Type
article
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article

Front Cover: Copper‐Catalyzed Sequential Azide‐Alkyne Cycloaddition (CuAAc) and Ullmann Coupling: A Tandem One‐Pot Synthesis of Quinazolino[3,2‐ c ][1,2,3] Triazolo[1,5‐ a ]‐Quinazolin‐14‐One (Eur. J. Org. Chem. 15/2026)

Gal Reddy Potuganti, Manjula Alla, Aravind Kandula, Shreya Patlolla
European Journal of Organic Chemistry
Quinazolinone synthesis and applications
article

Front Cover: Copper‐Catalyzed Sequential Azide‐Alkyne Cycloaddition (CuAAc) and Ullmann Coupling: A Tandem One‐Pot Synthesis of Quinazolino[3,2‐ c ][1,2,3] Triazolo[1,5‐ a ]‐Quinazolin‐14‐One (Eur. J. Org. Chem. 15/2026)

Gal Reddy Potuganti, Manjula Alla, Aravind Kandula, Shreya Patlolla
article en

Abstract

The Front Cover shows a copper-catalyzed tandem strategy that enables the efficient synthesis of triazole-fused quinazolinones through a multicomponent reaction of 2-bromophenyl quinazolinones, sodium azide, and terminal alkynes. Integrating CuAAC and Ulmann-type C–N coupling under mild, ligand-free conditions, this method yields diverse polycyclic N-heterocycles with broad substrate scope. More information can be found in the Research Article by M. Alla and co-workers (DOI: 10.1002/ejoc.202501064).

European Journal of Organic ChemistryVol. 29(15)
Indian Institute of Chemical Technology (IN), University of Oklahoma (US), Academy of Scientific and Innovative Research (IN)
Openalex Percentile: Top 8%
Quinazolinone synthesis and applications
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