VectorSage: Enhancing PubMed Article Retrieval with Advanced Semantic Search

Abstract The exponential growth of academic literature has presented unprecedented opportunities. However, it also underscores the need for advanced search methodologies to support efficient knowledge discovery. While effective for structured queries, traditional keyword-based search engines often struggle with the inherent variability of language, where the same concept can be expressed in many ways, leading to incomplete or imprecise retrieval of relevant research. Another issue that must be considered is that of lexical ambiguity, such as polysemy or homonymy, whereby several words and abbreviations can have multiple meanings. This results in items placed in the results list that are irrelevant to the search context. Recent advances in natural language processing have enabled semantic similarity techniques that move beyond basic text matching toward context-aware search. We developed VectorSage (https://vectorsage.nube.uni-greifswald.de/), an advanced biomedical search system for retrieving PubMed abstracts using a hybrid approach that combines term relevance scoring with embedding-based semantic similarity. VectorSage employs a global ranking mechanism to enhance further search relevance by sorting the retrieved documents, ensuring a balance between semantic relevance and keyword specificity. This method enables efficient literature exploration and knowledge discovery.

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Publication Details

Journal
Bioinformatics Advances
Published
2026-04-21
DOI
https://doi.org/10.1093/bioadv/vbag116
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00
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article

VectorSage: Enhancing PubMed Article Retrieval with Advanced Semantic Search

Rahul Brahma, Lars Kaderali, Mehdi Lotfi, Yasas Wijesekara et al.
Bioinformatics Advances
Biomedical Text Mining and Ontologies
article

VectorSage: Enhancing PubMed Article Retrieval with Advanced Semantic Search

Rahul Brahma, Lars Kaderali, Mehdi Lotfi, Yasas Wijesekara, Marcus Vollmer
article en

Abstract

Abstract The exponential growth of academic literature has presented unprecedented opportunities. However, it also underscores the need for advanced search methodologies to support efficient knowledge discovery. While effective for structured queries, traditional keyword-based search engines often struggle with the inherent variability of language, where the same concept can be expressed in many ways, leading to incomplete or imprecise retrieval of relevant research. Another issue that must be considered is that of lexical ambiguity, such as polysemy or homonymy, whereby several words and abbreviations can have multiple meanings. This results in items placed in the results list that are irrelevant to the search context. Recent advances in natural language processing have enabled semantic similarity techniques that move beyond basic text matching toward context-aware search. We developed VectorSage (https://vectorsage.nube.uni-greifswald.de/), an advanced biomedical search system for retrieving PubMed abstracts using a hybrid approach that combines term relevance scoring with embedding-based semantic similarity. VectorSage employs a global ranking mechanism to enhance further search relevance by sorting the retrieved documents, ensuring a balance between semantic relevance and keyword specificity. This method enables efficient literature exploration and knowledge discovery.

Bioinformatics Advances
Universitätsmedizin Greifswald (DE), Universität Greifswald (DE)
Quality Education
Openalex Percentile: Top 7%
Biomedical Text Mining and Ontologies
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