Looking Beyond Dose: Identifying Responders and Non-Responders to RehaCom Computerized Cognitive Rehabilitation in Progressive MS—The CogEx Study
= .71).ConclusionProcessing speed gains in progressive MS were related to both module-specific progression and participant characteristics, supporting a precision approach to cognitive rehabilitation that tailors training content to individual cognitive profiles. This study is a secondary analysis of the CogEx trial (ClinicalTrials.gov Identifier: NCT03679468; https://clinicaltrials.gov/ct2/show/NCT03679468).
Authors
- M Filippi
- Jeremy Chataway (ORCID: https://orcid.org/0000-0001-7286-6901)
- Nancy D. Chiaravalloti (ORCID: https://orcid.org/0000-0003-2943-7567)
- Cecilia Meza (ORCID: https://orcid.org/0009-0002-8553-0440)
- Silvana L. Costa (ORCID: https://orcid.org/0000-0002-5653-0153)
- Rachel Farrell (ORCID: https://orcid.org/0000-0002-2767-3382)
- Amber R. Salter (ORCID: https://orcid.org/0000-0002-1088-110X)
- Peter Feys (ORCID: https://orcid.org/0000-0002-5680-5495)
- Ulrik Dalgas (ORCID: https://orcid.org/0000-0003-4132-2789)
- Brian M. Sandroff (ORCID: https://orcid.org/0000-0002-2013-7632)
- R. Hernandez (ORCID: https://orcid.org/0000-0003-3143-682X)
- Maria Assunta Rocca (ORCID: https://orcid.org/0000-0003-2358-4320)
- Jennifer Freeman
- Matilde Inglese
- Giampaolo Brichetto
- Anthony Feinstein
- Robert W. Motl
- Gary Cutter
- Maria Pia Amato
- John DeLuca
Institutions
- Rutgers, The State University of New Jersey (US)
- St. Michael's Hospital (CA)
- Sunnybrook Health Science Centre (CA)
- Vita-Salute San Raffaele University (IT)
- Queen Mary University of London (GB)
- University of Toronto (CA)
- Aarhus University (DK)
- Kessler Foundation (US)
- Health Sciences Centre (CA)
- University of Alabama at Birmingham (US)
- National Institute for Health and Care Research (GB)
- University of Illinois Chicago (US)
- Associazione Italiana Sclerosi Multipla (IT)
- National Hospital for Neurology and Neurosurgery (GB)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Statistical Research (United States) (US)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- Rutgers New Jersey Medical School (US)
- University of Florence (IT)
- University College London (GB)
- University of Genoa (IT)
- Hasselt University (BE)
- University of Plymouth (GB)
Publication Details
- Journal
- Neurorehabilitation and neural repair
- Published
- 2026-04-25
- DOI
- https://doi.org/10.1177/15459683261432556
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Multiple Sclerosis Society of Canada