Comparative Efficacy of Two Defocus Soft Contact Lenses on Axial Length and Choroid in High Myopic Adolescents

BACKGROUND: To compare the 1-year myopia control efficacy of two defocus soft contact lenses (SCLs) versus single-vision spectacles in high myopic adolescents (spherical equivalent refraction [SER] of 6.00 diopters or more). METHODS: 237 participants were randomised into three groups: peripheral gradual defocus SCLs (Group A), multipoint defocus SCLs (Group B) and single-vision spectacles (Group C), with 12-month follow-up. Outcomes included axial length change (ΔAL), SER change (ΔSER), choroidal thickness (CT) and choroidal vascular density (VDCC). RESULTS: = 0.35, p value less than 0.001). CONCLUSION: Multipoint defocus SCLs outperform other methods in controlling high myopia and improving choroidal parameters.