Niosomes: A Novel Vesicular Drug Delivery System

Abstract A phenomenon known as "drug targeting" occurs when a medication is dispersed throughout the body in such a way that it interacts with the target tissue at the cellular or subcellular level to produce a desired therapeutic response at a desired site while avoiding unwanted interactions at other sites. Niosomes and other contemporary drug delivery system targeting techniques can do this. Niosomes are nonionic surfactant vesicles that are produced by hydrating synthetic nonionic surfactants, either with or without the addition of lipids or cholesterol. Both hydrophilic and lipophilic medications can be captured by niosomes, which can also prolong the drug's circulation throughout the body. It is anticipated that encapsulating a medication in a vesicular system may increase the drug's duration in the systemic circulation, improve its penetration into the target tissue, and possibly lessen toxicity if selective absorption is possible.The niosome's structure, benefits, drawbacks, preparation and characterisation techniques, etc. are all covered in this review article. Keywords: Niosomes, Non-ionic Surfactants, Hydrophilic, Applications, Methods of Preparation