The effect of a two-week low glycaemic index, higher fibre diet versus high glycaemic index diet on body composition, ectopic lipids, inflammatory biomarkers, gastrointestinal hormones and gut microbiota in metabolic dysfunction-associated steatotic

, p = 0.017), as well as increased pre-meal appetite scores during the middle of the diet period and decreased interleukin 6; IL-6 (-0.9 pg/mL) and glucagon (-13.7 pg/mL) levels (all p < 0.05). In agreement with previous work in healthy participants, this study suggests that LGI diets reduce liver fat in patients with MASLD and may be an important factor in preventative care. REGISTRATION: This trial was registered on the website of ClinicalTrials.gov, number NCT04415632.