Interfacial Proton‐Coupled Electron Transfer Reverses Water Inhibition for Selective 5‐hydroxymethylfurfural Hydrogenation
-induced electronic modulation transforms proximal lattice Fe into strong Lewis acids to polarize bulk water, creating a continuous lateral proton shuttle to the adsorbed HMF. This orthogonal PCET system drastically boosts electron selectivity from 10.6% (pristine nZVI) to 81.6%, achieving >95% HMF conversion (20-150 mM) with >95% BHMF selectivity under ambient conditions, outperforming pristine nZVI (<10% conversion) by orders of magnitude. This work demonstrates that engineering interfacial PCET pathways can reverse classical solvent inhibition, opening a general route for efficient aqueous hydrogenation.
Authors
- Minzi Liao
- Jinming Luo (ORCID: https://orcid.org/0000-0001-8698-7624)
- Weiwei Ma (ORCID: https://orcid.org/0000-0001-7016-5044)
- Haopeng Pei
- Hui Li (ORCID: https://orcid.org/0000-0001-9198-3951)
- Guangming Zhan (ORCID: https://orcid.org/0000-0001-9485-3458)
- Yinghao Li (ORCID: https://orcid.org/0000-0001-9584-8159)
- Y L Pan
- Sicong Ma
- Long Zhao
- Chenglin Hao
- Lizhi Zhang (ORCID: https://orcid.org/0000-0002-6842-9167)
- Bing Zhou
Institutions
- Shanghai Jiao Tong University (CN)
- Central China Normal University (CN)
- East China Normal University (CN)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2026-04-24
- DOI
- https://doi.org/10.1002/anie.5203276
- Primary Topic
- Catalysis for Biomass Conversion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China
- National Key Research and Development Program of China