Constructing an efficient synthesis pathway in peroxisomes to boost β-myrcene production in yeast
-myrcene titer to 4.7 g/L, which represents the highest level yet reported. This work provides a comprehensive framework for engineering yeast cell factories, highlighting the ability of integrated metabolic engineering to enhance high-value monoterpene production.
Authors
- Wenhai Xiao (ORCID: https://orcid.org/0000-0001-9427-6881)
- Jingyu Chang
- Yujie Shu (ORCID: https://orcid.org/0009-0007-5083-8425)
- Mingdong Yao
- Jia Wang
- Ying Wang
- Tianyu Dong
- Yingjin Yuan
Institutions
- Tianjin University (CN)
- Tianjin Synthetic Material Research Institute (China) (CN)
- Intelligent Synthetic Biology Center (KR)
- State Key Laboratory of Synthetic Chemistry (CN)
Publication Details
- Journal
- Synthetic and Systems Biotechnology
- Published
- 2026-04-25
- DOI
- https://doi.org/10.1016/j.synbio.2026.04.008
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China