EEG responses to auditory stimuli are less context-dependent in preschoolers with autism spectrum disorder compared to typical development
= .008). These findings suggested altered context-dependent modulation of sensory input in ASD. Lay Summary: Many children with autism show differences in how they process sounds. Using sound patterns in which loudness gradually increased and decreased over time, like many real-world sounds, we found that children with autism showed less neural differentiation between increasing and decreasing sounds. This finding suggested that the brain may process changes in sound differently in autism, particularly in how it adjusts to sounds as they change over time, which could contribute to the sensory challenges many children with autism experience in daily life.
Authors
- Jeffrey P. Gavornik (ORCID: https://orcid.org/0000-0001-8420-8973)
- April R. Levin (ORCID: https://orcid.org/0000-0003-4192-4720)
- Gerardo Parra (ORCID: https://orcid.org/0009-0006-4285-0371)
- Celia Tam
- Nancy Sullivan
- Damla Senturk
- Meiwen Shao (ORCID: https://orcid.org/0009-0008-4118-3938)
- Katie A. McNair (ORCID: https://orcid.org/0000-0001-8707-0826)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
- University of California, Los Angeles (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-04-25
- DOI
- https://doi.org/10.64898/2026.04.17.26350631
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- International Research Center for Neurointelligence, University of Tokyo
- National Institute of Neurological Disorders and Stroke