Photocatalytic and Palladium‐Catalyzed Synthesis of Thioglycoside‐1,2,4‐Triazole Derivatives

This study presents an efficient approach for the di‐functionalization of 1,2,4‐triazoles with thiosugars, combining photochemical processes and metal‐catalyzed coupling reactions under mild conditions. Exploiting the dual reactivity of the selected 1,2,4‐triazoles, this strategy enables selective and versatile transformations, affording a new family of 1,2,4‐triazole derivatives conjugated with thiosugars with potential for further exploration in biologically relevant studies.

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Publication Details

Journal
European Journal of Organic Chemistry
Published
2026-04-24
DOI
https://doi.org/10.1002/ejoc.70493
Primary Topic
Click Chemistry and Applications
Type
article
Field-Weighted Citation Impact
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article

Photocatalytic and Palladium‐Catalyzed Synthesis of Thioglycoside‐1,2,4‐Triazole Derivatives

Franck Le Bideau, Mohamed Lotfi Efrit, Samir Messaoudi, Oumayma Ben Jaballah
European Journal of Organic Chemistry
Click Chemistry and Applications
article

Photocatalytic and Palladium‐Catalyzed Synthesis of Thioglycoside‐1,2,4‐Triazole Derivatives

Franck Le Bideau, Mohamed Lotfi Efrit, Samir Messaoudi, Oumayma Ben Jaballah
article en

Abstract

This study presents an efficient approach for the di‐functionalization of 1,2,4‐triazoles with thiosugars, combining photochemical processes and metal‐catalyzed coupling reactions under mild conditions. Exploiting the dual reactivity of the selected 1,2,4‐triazoles, this strategy enables selective and versatile transformations, affording a new family of 1,2,4‐triazole derivatives conjugated with thiosugars with potential for further exploration in biologically relevant studies.

European Journal of Organic Chemistry
Centre National de la Recherche Scientifique (FR), École Polytechnique (FR), École Nationale Supérieure de Techniques Avancées (FR), Laboratoire de Synthèse Organique (FR), Tunis El Manar University (TN)
Openalex Percentile: Top 14%
Click Chemistry and Applications
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