Gut Microbiome and Psychoneurological Symptoms Among Patients With Colorectal Cancer and Their Caregivers: A Pilot Study

CRC patients actively on chemotherapy demonstrated reduced diversity and depletion of beneficial taxa that may contribute to heightened PNS. Caregivers, despite healthier profiles, reported substantial symptom burden that were linked to gut microbiome features, highlighting dyadic interdependence and the potential for microbiome-targeted, dyadic interventions in survivorship care.

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Publication Details

Journal
Biological Research For Nursing
Published
2026-04-24
DOI
https://doi.org/10.1177/10998004261447509
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Gut Microbiome and Psychoneurological Symptoms Among Patients With Colorectal Cancer and Their Caregivers: A Pilot Study

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Gut Microbiome and Psychoneurological Symptoms Among Patients With Colorectal Cancer and Their Caregivers: A Pilot Study

Canhua Xiao, Olatunji B. Alese, Zahra Amirkhanzadeh Barandouzi, Madelyn C. Houser, Jinbing Bai, Yufen Lin, Deborah W. Bruner, Sindile Mathebula, Olumide Gbolahan
article en

Abstract

CRC patients actively on chemotherapy demonstrated reduced diversity and depletion of beneficial taxa that may contribute to heightened PNS. Caregivers, despite healthier profiles, reported substantial symptom burden that were linked to gut microbiome features, highlighting dyadic interdependence and the potential for microbiome-targeted, dyadic interventions in survivorship care.

Biological Research For Nursing
Emory University (US)
Oncology Nursing Foundation
Openalex Percentile: Top 13%
Gut microbiota and health
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Gut Microbiome and Psychoneurological Symptoms Among Patients With Colorectal Cancer and Their Caregivers: A Pilot Study — Canhua Xiao, Olatunji B. Alese, et al. · Biological Research For Nursing (2026) | TGRS Research Map | TGRS