Palliative Care in Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomised Controlled Trials and Associations With Intervention and Patient Characteristics

= 35%] and depression [MD HADS-D: -0.44 (95% CI -0.75 to -0.13)]. No clear differences were observed between intervention modes. Longer interventions (>12 weeks) and interventions targeting patients with advanced HF symptoms (NYHA III/IV ≥70%) were associated with greater improvement in KCCQ and reduction in hospitalisation respectively. No differences in outcomes were observed by gender distribution.ConclusionsPalliative care reduces hospitalisations, improves QoL and mental health in HF. Longer interventions and those targeting patients with advanced symptoms were linked to differences in outcomes, whereas mode of intervention and gender did not appear to impact outcomes.