Visualizing Newly Synthesized Proteins and Their Degradation Dynamics by Using Long-Wavelength-Emitting Fluorescent Dye–DBCO Conjugates
suggested that senescent cells have a lower protein degradation ability than nonsenescent cells. These methods should be useful for investigating protein homeostasis in living cells.
Authors
- Yoshihiko Kuchitsu (ORCID: https://orcid.org/0000-0003-0422-8056)
- Fan‐Yan Wei (ORCID: https://orcid.org/0000-0002-4843-724X)
- Tomohiko Taguchi (ORCID: https://orcid.org/0000-0003-0464-6370)
- H. Ohno (ORCID: https://orcid.org/0009-0008-0177-782X)
- Sota Yamada (ORCID: https://orcid.org/0000-0002-5083-5650)
- Kenjiro Hanaoka (ORCID: https://orcid.org/0000-0003-0797-4038)
- Orie Takayama
- Eita Sasaki (ORCID: https://orcid.org/0000-0002-8202-4465)
- Shun Sumitani
Institutions
- Tohoku University (JP)
- Keio University (JP)
- Institute of Life Sciences (IN)
- Institute of Aging (CA)
Publication Details
- Journal
- Bioconjugate Chemistry
- Published
- 2026-04-24
- DOI
- https://doi.org/10.1021/acs.bioconjchem.5c00645
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Keio University
- Japan Society for the Promotion of Science
- Core Research for Evolutional Science and Technology