Electronic Structure-Engineered Vanadium Carbide MXene Nanocatalyst Enables Multimodal Reactive Species Scavenging for Stem Cell Regulation

C demonstrates high catalytic stability over multiple cycles and preserves endogenous defense pathways without inducing cytotoxicity. Under oxidative stress, the nanocatalyst protects mesenchymal stem cells by suppressing reactive species-induced cell damage and restoring adhesion, proliferation, and migratory capacity while simultaneously promoting osteogenic differentiation. This study establishes a robust strategy for electronic-structure engineering of vanadium-based MXene biocatalysts and highlights their potential as high-performance platforms for stem cell protection and redox microenvironment regulation.

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Publication Details

Journal
Langmuir
Published
2026-04-24
DOI
https://doi.org/10.1021/acs.langmuir.6c00237
Primary Topic
MXene and MAX Phase Materials
Type
article
Field-Weighted Citation Impact
0.00

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article

Electronic Structure-Engineered Vanadium Carbide MXene Nanocatalyst Enables Multimodal Reactive Species Scavenging for Stem Cell Regulation

Jinzheng Liu, Zhe Hao, F S Zhang, Libing Zhang et al.
Langmuir
MXene and MAX Phase Materials
article

Electronic Structure-Engineered Vanadium Carbide MXene Nanocatalyst Enables Multimodal Reactive Species Scavenging for Stem Cell Regulation

Jinzheng Liu, Zhe Hao, F S Zhang, Libing Zhang, Huan Guo, Ziyan Yu, Shou Liu, Ruizhong Zhang, Xiyan Li
article en

Abstract

C demonstrates high catalytic stability over multiple cycles and preserves endogenous defense pathways without inducing cytotoxicity. Under oxidative stress, the nanocatalyst protects mesenchymal stem cells by suppressing reactive species-induced cell damage and restoring adhesion, proliferation, and migratory capacity while simultaneously promoting osteogenic differentiation. This study establishes a robust strategy for electronic-structure engineering of vanadium-based MXene biocatalysts and highlights their potential as high-performance platforms for stem cell protection and redox microenvironment regulation.

LangmuirVol. 42(17)
Tianjin University (CN), Nankai University (CN), Tianjin Academy of Fine Arts (CN), Tianjin Renai College
National Natural Science Foundation of China
Openalex Percentile: Top 19%
MXene and MAX Phase Materials
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