Acral Plantar Melanoma Mimicking a Diabetic Foot Ulcer in a Nonagenarian: A Case Report

Acral melanoma on the plantar surface may be clinically overlooked and can resemble common causes of plantar ulceration. In patients with diabetes, chronic plantar lesions are often managed as diabetic foot ulcers, which can delay consideration of alternative diagnoses. We report the case of a very elderly woman with diabetes whose plantar lesion was initially treated as a diabetic foot ulcer but later evolved with features concerning for malignancy. Histopathology confirmed deeply invasive ulcerated acral melanoma. This case highlights the importance of maintaining suspicion for malignant mimics in non-healing plantar lesions and supports early biopsy when a presumed diabetic foot ulcer behaves atypically or fails to improve with appropriate care.

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Publication Details

Journal
Cureus
Published
2026-04-24
DOI
https://doi.org/10.7759/cureus.107644
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Acral Plantar Melanoma Mimicking a Diabetic Foot Ulcer in a Nonagenarian: A Case Report

Priscilla Márquez, Gerardo Bascuñán, Monserrat Cendoya, Diego Guarda
Cureus
Cutaneous Melanoma Detection and Management
article

Acral Plantar Melanoma Mimicking a Diabetic Foot Ulcer in a Nonagenarian: A Case Report

Priscilla Márquez, Gerardo Bascuñán, Monserrat Cendoya, Diego Guarda
article en

Abstract

Acral melanoma on the plantar surface may be clinically overlooked and can resemble common causes of plantar ulceration. In patients with diabetes, chronic plantar lesions are often managed as diabetic foot ulcers, which can delay consideration of alternative diagnoses. We report the case of a very elderly woman with diabetes whose plantar lesion was initially treated as a diabetic foot ulcer but later evolved with features concerning for malignancy. Histopathology confirmed deeply invasive ulcerated acral melanoma. This case highlights the importance of maintaining suspicion for malignant mimics in non-healing plantar lesions and supports early biopsy when a presumed diabetic foot ulcer behaves atypically or fails to improve with appropriate care.

Cureus
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Cutaneous Melanoma Detection and Management
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