High-Altitude Exercise Performance and Acute Mountain Sickness Unchanged Following Cold Water Habituation
= 0.030). Two-mile time trial performance and AMS symptomology were both unchanged by repeated CWI compared to TN. Habituation to repeated cold-water immersion does not advantageously cross adapt those subsequently exposed to hypobaric hypoxia. Instead, CWI heightened early altitude ventilatory and cardiovascular strain during submaximal exercise.
Authors
- Samantha J. Goldenstein (ORCID: https://orcid.org/0009-0000-9716-6944)
- Benjamin J. Ryan (ORCID: https://orcid.org/0000-0001-5848-6988)
- Kathryn G. McCarthy (ORCID: https://orcid.org/0000-0003-0139-2870)
- Aaron R. Caldwell (ORCID: https://orcid.org/0000-0002-4541-6283)
- David H. Gonzalez Rojas
- Afton D. Seeley (ORCID: https://orcid.org/0000-0002-3514-1423)
- Gabrielle E. W. Giersch (ORCID: https://orcid.org/0000-0002-6603-4399)
- Andrew M. Greenfield (ORCID: https://orcid.org/0000-0001-9458-9853)
- K. Riley Connor (ORCID: https://orcid.org/0009-0003-0033-7711)
- Billie K. Alba (ORCID: https://orcid.org/0000-0001-6503-6053)
- Roy M. Salgado (ORCID: https://orcid.org/0000-0002-4306-4130)
- Thomas A. Mayer (ORCID: https://orcid.org/0000-0002-1581-9196)
- John W. Castellani (ORCID: https://orcid.org/0000-0002-6728-463X)
- Shaun C. Brazelton (ORCID: https://orcid.org/0009-0008-4132-5051)
- MariaLena A. Shaw
- Karleigh E. Bradbury
- Benjamin A. Fry
- Molly E Heikkinen
- Phillip O. Bodurtha (ORCID: https://orcid.org/0009-0009-5837-6784)
Institutions
- U.S. Army Research Institute of Environmental Medicine (US)
- Oak Ridge Associated Universities (US)
- Oak Ridge Institute for Science and Education
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Published
- 2026-04-24
- DOI
- https://doi.org/10.1152/ajpregu.00149.2025
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00