Expert Opinion on the Diagnosis and Treatment of Hematologic Malignancies During Pregnancy
The diagnosis and treatment of hematologic malignancies has undergone significant advancements over the past few decades, resulting in enhanced outcomes. For hematologic malignancies diagnosed during pregnancy, this poses new questions. As possibilities continue to expand and the rising global incidence results in an increasing number of diagnoses within the pregnant population, there is a pressing need to gain a deeper understanding of the potential options for pregnant women and the impact on the newborn. As knowledge of the effects of cancer treatment increases, more women are receiving adequate cancer diagnosis and treatment during pregnancy. This paper presents an expert opinion on the use of diagnostic modalities and treatment options, including chemotherapy, radiation therapy, and immunotherapy, for acute leukemia, Hodgkin lymphoma, non-Hodgkin lymphoma, myeloproliferative neoplasms, aplastic anemia, and multiple myeloma during pregnancy.
Authors
- Frédéric Amant (ORCID: https://orcid.org/0000-0002-5452-4905)
- Daan Dierickx (ORCID: https://orcid.org/0000-0002-8917-022X)
- Mar Bellido (ORCID: https://orcid.org/0000-0001-9864-5816)
- Markus Alber
- Andres Ferbér
- Kristel Van Calsteren (ORCID: https://orcid.org/0000-0002-2438-6783)
- Elyce Cardonick (ORCID: https://orcid.org/0000-0003-2203-3367)
- Álvaro Cabrera-García (ORCID: https://orcid.org/0000-0001-7856-2044)
- Adinda Baten (ORCID: https://orcid.org/0000-0001-7104-7808)
- Andrew M. Evens (ORCID: https://orcid.org/0000-0002-6900-1824)
- Ivan R. Vogelius (ORCID: https://orcid.org/0000-0002-8877-1218)
- Monica Fumagalli (ORCID: https://orcid.org/0000-0002-0186-0710)
- Lena Specht (ORCID: https://orcid.org/0000-0002-6902-2190)
- E Lampka
- V Vandecaveye
- Joosje H. Heimovaara
Institutions
- University Medical Center Groningen (NL)
- Thomas Jefferson University (US)
- University of Groningen (NL)
- University of Milan (IT)
- Heidelberg University (DE)
- Universitair Ziekenhuis Leuven (BE)
- University Hospital Heidelberg (DE)
- Johnson University (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Universidad México Contemporáneo (MX)
- IMEC (BE)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Hospital Regional de Alta Especialidad del Bajío (MX)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Cooper University Health Care (US)
- KU Leuven (BE)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2026-04-24
- DOI
- https://doi.org/10.1200/jco-25-02351
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00