Staying IgD positive in a challenging environment
The nasopharyngeal tissues provide a frontline defense against airborne exposure to viruses, bacteria, and allergens. In this issue of JEM, Tachó-Piñot et al. (https://doi.org/10.1084/jem.20251752) show that mutated IgD+ B cell subsets populate epithelial areas of nasopharyngeal mucosa, ready to tackle a multitude of antigenic targets.
Authors
- Kim L. Good‐Jacobson (ORCID: https://orcid.org/0000-0003-1891-7274)
Institutions
- Discovery Institute (US)
- Monash University (AU)
Publication Details
- Journal
- The Journal of Experimental Medicine
- Published
- 2026-04-10
- DOI
- https://doi.org/10.1084/jem.20260394
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health and Medical Research Council