Effect of Bacillus coagulans DSM 32016 (TechnoSpore®) Supplementation on Growth Performance and Selected Blood Parameters and Serum Urea in Weaning Danube White Pigs

The present study evaluated the effects of dietary supplementation with Bacillus coagulans DSM 32016 on growth performance, hematological and biochemical parameters, and nitrogen metabolism in weaned Danube White pigs reared under standard production conditions. While supplementation did not result in statistically significant changes in average daily gain (ADG), feed conversion ratio (FCR), hematological indices, or serum lipid profile, numerical trends indicated slightly higher ADG, improved FCR, and subtle stabilization of hematological parameters in the probiotic supplemented group. Notably, serum urea concentration was significantly reduced (3.78 vs. 3.21 mmol/L; p = 0.017; Cohen’s d = 1.01), suggesting a potential positive effect on nitrogen metabolism and protein utilization efficiency. These findings are consistent with previous reports that probiotics may exert beneficial physiological effects even in the absence of statistically significant systemic changes. The observed trends highlight the potential of Bacillus coagulans to support growth performance and metabolic efficiency in Danube White pigs, emphasizing the importance of breed and age-specific responses in probiotic supplementation.