Improvement of young-onset dilated cardiomyopathy by successful resection of pheochromocytoma

Pheochromocytoma-induced cardiomyopathy is a rare but serious condition caused by excessive catecholamine release, leading to heart failure and life-threatening hemodynamic instability. Managing such cases requires a delicate balance of treatments to stabilize the cardiovascular system while preparing for tumor removal. A 16-year-old boy came to the hospital with severe abdominal pain, palpitations, and breathlessness, which progressively worsened despite multiple medical consultations. He was diagnosed with dilated cardiomyopathy and severe heart failure and was worked up extensively for the same. He was planned for heart transplantation after stabilization. However, a non-contrast computed tomography of the abdomen done as part of the pre-operative workup showed an adrenal lesion, and further testing revealed an adrenal pheochromocytoma. His treatment required careful adjustments of medications to support his heart while ensuring safe tumor resection. Alpha-blockers, inotropes, and fluid management were carefully balanced to prevent complications. A highly coordinated team of endocrinologists, cardiologists, anesthesiologists, and surgeons worked together to optimize his condition before surgery. He underwent a successful open adrenalectomy, and with intensive postoperative care, his left ventricular function gradually improved. A year later, he remains symptom-free, with his catecholamine levels returning to normal and ejection fraction improving from 10% to 40%. This case underscores the importance of personalized care and a multidisciplinary approach in managing pheochromocytoma-related heart failure, ensuring both surgical success and long-term recovery.

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Publication Details

Journal
Journal of Pediatric Endocrinology and Diabetes
Published
2026-04-22
DOI
https://doi.org/10.25259/jped_57_2025
Citations
1
Primary Topic
Adrenal and Paraganglionic Tumors
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article
Field-Weighted Citation Impact
26.86
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article

Improvement of young-onset dilated cardiomyopathy by successful resection of pheochromocytoma

Pushpender Khatana, Parjeet Kaur, Anand Rajendran, Vaibhav Joshi et al.
1 citations
Journal of Pediatric Endocrinology and Diabetes
Adrenal and Paraganglionic Tumors
26.86
article

Improvement of young-onset dilated cardiomyopathy by successful resection of pheochromocytoma

Pushpender Khatana, Parjeet Kaur, Anand Rajendran, Vaibhav Joshi, Navein John Thomas John
article en
1 citations

Abstract

Pheochromocytoma-induced cardiomyopathy is a rare but serious condition caused by excessive catecholamine release, leading to heart failure and life-threatening hemodynamic instability. Managing such cases requires a delicate balance of treatments to stabilize the cardiovascular system while preparing for tumor removal. A 16-year-old boy came to the hospital with severe abdominal pain, palpitations, and breathlessness, which progressively worsened despite multiple medical consultations. He was diagnosed with dilated cardiomyopathy and severe heart failure and was worked up extensively for the same. He was planned for heart transplantation after stabilization. However, a non-contrast computed tomography of the abdomen done as part of the pre-operative workup showed an adrenal lesion, and further testing revealed an adrenal pheochromocytoma. His treatment required careful adjustments of medications to support his heart while ensuring safe tumor resection. Alpha-blockers, inotropes, and fluid management were carefully balanced to prevent complications. A highly coordinated team of endocrinologists, cardiologists, anesthesiologists, and surgeons worked together to optimize his condition before surgery. He underwent a successful open adrenalectomy, and with intensive postoperative care, his left ventricular function gradually improved. A year later, he remains symptom-free, with his catecholamine levels returning to normal and ejection fraction improving from 10% to 40%. This case underscores the importance of personalized care and a multidisciplinary approach in managing pheochromocytoma-related heart failure, ensuring both surgical success and long-term recovery.

Journal of Pediatric Endocrinology and DiabetesVol. 6
Medanta The Medicity (IN), Asian Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 0%
Adrenal and Paraganglionic Tumors
26.86
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Improvement of young-onset dilated cardiomyopathy by successful resection of pheochromocytoma — Pushpender Khatana, Parjeet Kaur, et al. · Journal of Pediatric Endocrinology and Diabetes (2026) | TGRS Research Map | TGRS