Clathrin adaptor <scp>EPSIN1</scp> ( <scp>EPS1</scp> ) modulates plasma membrane abundance of <scp>PLEIOTROPIC DRUG RESISTANCE PDR9</scp> for effective hormone homeostasis
The cellular machinery that directs the indole-3-butyric acid (IBA) effluxer PLEIOTROPIC DRUG RESISTANCE 9 (PDR9) to the outer plasma membrane (PM) domain of the root epidermis remains poorly understood. This study combines biochemical fractionation, live-cell imaging, and physiological assays to identify the trans-Golgi Network-localized clathrin adaptor EPSIN1 (EPS1) as a novel modulator of PDR9 abundance at the root PM for IBA-dependent physiological processes. These findings expand EPS1's roles from plant immunity to hormone homeostasis, thereby advancing the limited understanding of biological functions for plant EPSINs.
Authors
- Lucia C. Strader (ORCID: https://orcid.org/0000-0002-7600-7204)
- Antje Heese (ORCID: https://orcid.org/0000-0003-2711-6153)
- Nga T. Nguyen (ORCID: https://orcid.org/0000-0003-1016-3068)
- Scott C. Peck (ORCID: https://orcid.org/0000-0002-9804-1366)
- Erica D. LaMontagne (ORCID: https://orcid.org/0000-0003-2654-5095)
- Gabriela F. Kauffman (ORCID: https://orcid.org/0000-0002-7167-1798)
- Margaret Vedra (ORCID: https://orcid.org/0000-0002-6794-145X)
Institutions
- Salk Institute for Biological Studies (US)
- University of Missouri (US)
Publication Details
- Journal
- New Phytologist
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1111/nph.71208
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.00