Evaluation of a numerical simulation for multibipolar radiofrequency ablation

INTRODUCTION: porcine liver model. A GPU-accelerated finite-difference time-domain (FDTD) simulation coupling the quasi-static Maxwell and Pennes' bioheat equations was implemented to model mbRFA. METHODS: mbRFA were performed using three internally cooled bipolar applicators. A saline-perfused glass tube was employed to simulate a standardized blood flow and positioned at five predefined distances from the ablation center in 2.5 mm increments. Simulated and experimental ablations were compared using area-, surface- and classification-based metrics on a standardized two-dimensional (2D) cross section to evaluate the model's predictive accuracy. RESULTS: ablations and the simulation were 0.92 (Dice coefficient) and 0.85 (Jaccard coefficient), respectively. Compared to the reference area, the simulation overestimated the ablation zone by 4% (false-positive regions) and underestimated it by 10% (false-negative regions). CONCLUSION: Overall, the numerical model demonstrated good spatial agreement with the experimental ablations, confirming its suitability for quantitative prediction of ablation geometry.

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Publication Details

Journal
International Journal of Hyperthermia
Published
2026-04-22
DOI
https://doi.org/10.1080/02656736.2026.2657470
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
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article

Evaluation of a numerical simulation for multibipolar radiofrequency ablation

Hanne Ballhausen, Kai S. Lehmann, David Sinden, Christian Rieder et al.
International Journal of Hyperthermia
Cardiac Arrhythmias and Treatments
article

Evaluation of a numerical simulation for multibipolar radiofrequency ablation

Hanne Ballhausen, Kai S. Lehmann, David Sinden, Christian Rieder, Ole Gemeinhardt, Franz Poch, Christina A. Neizert, Tobias Preußer
article en

Abstract

INTRODUCTION: porcine liver model. A GPU-accelerated finite-difference time-domain (FDTD) simulation coupling the quasi-static Maxwell and Pennes' bioheat equations was implemented to model mbRFA. METHODS: mbRFA were performed using three internally cooled bipolar applicators. A saline-perfused glass tube was employed to simulate a standardized blood flow and positioned at five predefined distances from the ablation center in 2.5 mm increments. Simulated and experimental ablations were compared using area-, surface- and classification-based metrics on a standardized two-dimensional (2D) cross section to evaluate the model's predictive accuracy. RESULTS: ablations and the simulation were 0.92 (Dice coefficient) and 0.85 (Jaccard coefficient), respectively. Compared to the reference area, the simulation overestimated the ablation zone by 4% (false-positive regions) and underestimated it by 10% (false-negative regions). CONCLUSION: Overall, the numerical model demonstrated good spatial agreement with the experimental ablations, confirming its suitability for quantitative prediction of ablation geometry.

International Journal of HyperthermiaVol. 43(1)
University of Bremen (DE), University Hospital Augsburg (DE), Humboldt-Universität zu Berlin (DE), Hasomed (Germany) (DE), Fraunhofer Institute for Digital Medicine (DE)
Openalex Percentile: Top 11%
Cardiac Arrhythmias and Treatments
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Evaluation of a numerical simulation for multibipolar radiofrequency ablation — Hanne Ballhausen, Kai S. Lehmann, et al. · International Journal of Hyperthermia (2026) | TGRS Research Map | TGRS