Physical mechanisms governing generalization and hallucination in deep learning for imaging through scattering media

), while hallucinations arise when this capacity is exceeded, resulting in unconstrained, non-physical predictions. We also identify residual ballistic light, if not negligible, as a stabilizing anchor, enabling robust predictions under scattering variability. Integrating experimental validation with wave-optics simulations, we establish a universal framework that links these phenomena, showing that strategic training on diverse physical mappings enhances generalization while suppressing hallucinations. This work bridges physics-driven interpretability with AI design, offering actionable strategies to develop reliable models for applications ranging from medical imaging through biological tissues to autonomous navigation in scattering environments.

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Publication Details

Journal
Nature Communications
Published
2026-04-23
DOI
https://doi.org/10.1038/s41467-026-72304-z
Primary Topic
Random lasers and scattering media
Type
article
Field-Weighted Citation Impact
0.00

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article

Physical mechanisms governing generalization and hallucination in deep learning for imaging through scattering media

Haofan Huang, Xuyu Zhang, Puxiang Lai, D Zhang et al.
Nature Communications
Random lasers and scattering media
article

Physical mechanisms governing generalization and hallucination in deep learning for imaging through scattering media

Haofan Huang, Xuyu Zhang, Puxiang Lai, D Zhang, Tianting Zhong, Honglin Liu, Shensheng Han, Songlin Zhuang
article en

Abstract

), while hallucinations arise when this capacity is exceeded, resulting in unconstrained, non-physical predictions. We also identify residual ballistic light, if not negligible, as a stabilizing anchor, enabling robust predictions under scattering variability. Integrating experimental validation with wave-optics simulations, we establish a universal framework that links these phenomena, showing that strategic training on diverse physical mappings enhances generalization while suppressing hallucinations. This work bridges physics-driven interpretability with AI design, offering actionable strategies to develop reliable models for applications ranging from medical imaging through biological tissues to autonomous navigation in scattering environments.

Nature Communications
Hong Kong Polytechnic University (HK), University of Shanghai for Science and Technology (CN), Shenzhen Polytechnic University (CN), Chinese Academy of Sciences (CN), Shanghai Institute of Optics and Fine Mechanics (CN), University of Chinese Academy of Sciences (CN)
National Natural Science Foundation of China, Innovation and Technology Commission, Hong Kong Polytechnic University, Science, Technology and Innovation Commission of Shenzhen Municipality
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Openalex Percentile: Top 6%
Random lasers and scattering media
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