Home environment conditions during childhood and psychosocial outcomes across three generations in Sweden: population based adoption-discordant sibling comparison study

OBJECTIVES: To examine if early adoption into a family with favourable home environment conditions reduces long term psychosocial risks and provides intergenerational benefits among individuals born to parents with psychiatric or behavioural problems. DESIGN: Population based adoption-discordant sibling comparison study. SETTING: Swedish registers of births between 1950 and 1980, with follow-up to 31 December 2020. PARTICIPANTS: Two samples of sibling pairs from at risk families: 4254 full siblings and 7796 maternal half siblings, who were or were not adopted before age 10 years. Offspring of these siblings (born 1965-2020) were also followed to assess intergenerational spillover effects. MAIN OUTCOME MEASURES: The variable of interest was adoption into non-biological families. Outcomes included psychiatric diagnoses, long term unemployment, receipt of social welfare, highest attained education (and upper secondary education ineligibility for generation 3), criminal convictions, and, among men, non-cognitive skills and general intelligence assessed at military conscription. RESULTS: 32.3% with psychiatric disorders), although the associations were weaker and less precisely estimated. This pattern of associations was similar in the maternal half sibling sample. CONCLUSIONS: Early adoption into a family with favourable home environment conditions was associated with moderate, enduring benefits across psychiatric, social, and cognitive outcomes, extending into the next generation. These results highlight the potential for environmental improvements during childhood to mitigate intergenerational disadvantage.

Authors

Institutions

Publication Details

Journal
BMJ
Published
2026-04-22
DOI
https://doi.org/10.1136/bmj-2025-087844
Primary Topic
Child Welfare and Adoption
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Home environment conditions during childhood and psychosocial outcomes across three generations in Sweden: population based adoption-discordant sibling comparison study

Mengping Zhou, Erik Pettersson, Isabell Brikell, Henrik Larsson et al.
BMJ
Child Welfare and Adoption
article

Home environment conditions during childhood and psychosocial outcomes across three generations in Sweden: population based adoption-discordant sibling comparison study

Mengping Zhou, Erik Pettersson, Isabell Brikell, Henrik Larsson, Brian M D’Onofrio, Zheng Chang, Ralf Kuja-Halkola, Zhenxin Liao, Paul Lichtenstein
article en

Abstract

OBJECTIVES: To examine if early adoption into a family with favourable home environment conditions reduces long term psychosocial risks and provides intergenerational benefits among individuals born to parents with psychiatric or behavioural problems. DESIGN: Population based adoption-discordant sibling comparison study. SETTING: Swedish registers of births between 1950 and 1980, with follow-up to 31 December 2020. PARTICIPANTS: Two samples of sibling pairs from at risk families: 4254 full siblings and 7796 maternal half siblings, who were or were not adopted before age 10 years. Offspring of these siblings (born 1965-2020) were also followed to assess intergenerational spillover effects. MAIN OUTCOME MEASURES: The variable of interest was adoption into non-biological families. Outcomes included psychiatric diagnoses, long term unemployment, receipt of social welfare, highest attained education (and upper secondary education ineligibility for generation 3), criminal convictions, and, among men, non-cognitive skills and general intelligence assessed at military conscription. RESULTS: 32.3% with psychiatric disorders), although the associations were weaker and less precisely estimated. This pattern of associations was similar in the maternal half sibling sample. CONCLUSIONS: Early adoption into a family with favourable home environment conditions was associated with moderate, enduring benefits across psychiatric, social, and cognitive outcomes, extending into the next generation. These results highlight the potential for environmental improvements during childhood to mitigate intergenerational disadvantage.

BMJVol. 393
Peking University (CN), Örebro University (SE), Karolinska Institutet (SE), China National Pharmaceutical Group Corporation (China) (CN), Indiana University Bloomington (US), Peking University International Hospital (CN)
Vetenskapsrådet, Forskningsrådet om Hälsa, Arbetsliv och Välfärd, Svenska Läkaresällskapet
Openalex Percentile: Top 6%
Child Welfare and Adoption
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.