Home environment conditions during childhood and psychosocial outcomes across three generations in Sweden: population based adoption-discordant sibling comparison study
OBJECTIVES: To examine if early adoption into a family with favourable home environment conditions reduces long term psychosocial risks and provides intergenerational benefits among individuals born to parents with psychiatric or behavioural problems. DESIGN: Population based adoption-discordant sibling comparison study. SETTING: Swedish registers of births between 1950 and 1980, with follow-up to 31 December 2020. PARTICIPANTS: Two samples of sibling pairs from at risk families: 4254 full siblings and 7796 maternal half siblings, who were or were not adopted before age 10 years. Offspring of these siblings (born 1965-2020) were also followed to assess intergenerational spillover effects. MAIN OUTCOME MEASURES: The variable of interest was adoption into non-biological families. Outcomes included psychiatric diagnoses, long term unemployment, receipt of social welfare, highest attained education (and upper secondary education ineligibility for generation 3), criminal convictions, and, among men, non-cognitive skills and general intelligence assessed at military conscription. RESULTS: 32.3% with psychiatric disorders), although the associations were weaker and less precisely estimated. This pattern of associations was similar in the maternal half sibling sample. CONCLUSIONS: Early adoption into a family with favourable home environment conditions was associated with moderate, enduring benefits across psychiatric, social, and cognitive outcomes, extending into the next generation. These results highlight the potential for environmental improvements during childhood to mitigate intergenerational disadvantage.
Authors
- Mengping Zhou (ORCID: https://orcid.org/0000-0002-6117-0690)
- Erik Pettersson
- Isabell Brikell
- Henrik Larsson
- Brian M D’Onofrio
- Zheng Chang
- Ralf Kuja-Halkola
- Zhenxin Liao (ORCID: https://orcid.org/0009-0008-1373-4050)
- Paul Lichtenstein
Institutions
- Peking University (CN)
- Örebro University (SE)
- Karolinska Institutet (SE)
- China National Pharmaceutical Group Corporation (China) (CN)
- Indiana University Bloomington (US)
- Peking University International Hospital (CN)
Publication Details
- Journal
- BMJ
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1136/bmj-2025-087844
- Primary Topic
- Child Welfare and Adoption
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Vetenskapsrådet
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Svenska Läkaresällskapet