Comparative Evaluation of Remineralizing Agents on Hypersensitivity Scores in Molar Incisor Hypomineralization-affected Teeth: A Randomized Clinical Trial

fluoride application, fissure sealants, lozenges, restorations, stainless steel or esthetic crowns, and laser irradiation. 5ecently, various biodontic materials have been invented.One such material is surface prereacted glass-ionomer (S-PRG), which IntroductIonMolar incisor hypomineralization (MIH), a developmental defect of enamel, is known to involve the first permanent molars with or without involving the permanent incisors.This has gained the dental clinician's attention recently and has been found to be affecting populations with a prevalence of 2.4-40.2%depending on the different geographical areas. 1,2The term MIH was introduced by Weerheijm et al., is often misdiagnosed or goes unnoticed during examination, resulting in various complications such as pitting of enamel with yellow to brown opacities, hypersensitivity, difficulty in achieving anesthetic effects, and posteruptive breakdown of the tooth structure.Evidence suggests that the MIH-affected enamel consists of enamel that is 20% less mineralized and contains more protein. 3,4isruptive enamel surfaces are more prone to plaque adhesion, resulting in more incidence of dental caries and destruction of tooth structure exposing dental pulps.Additionally, such complications are more often associated with unesthetic appearances, painful episodes, and psychosocial issues among pediatric patients.Diagnosis and treatment of MIH become challenging due to its complex etiology; however, its early diagnosis and timely intervention must be followed with a conservative approach.As these teeth are more prone to caries and breakdown, they should be treated with utmost care.A variety of minimally invasive treatment options are recommended for MIH depending on its severity, ranging from application of remineralizing agents, varnishes, 1,