Synergistic antibacterial and osteogenic activities of GO/GelMA hydrogel for regenerating periodontal bone defects

Objective: experiments. Methods: validation. Results: results revealed that the 200 µg/mL GO/GelMA group achieved the most significant alveolar bone regeneration and the lowest levels of inflammatory factors. Conclusion: The GO/GelMA hydrogels, particularly at a GO concentration of 200 µg/mL, demonstrate excellent synergistic antibacterial and osteogenic properties, holding great promise for treating periodontitis-related bone defects.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2026-04-23
DOI
https://doi.org/10.3389/fbioe.2026.1744639
Primary Topic
Graphene and Nanomaterials Applications
Type
article
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article

Synergistic antibacterial and osteogenic activities of GO/GelMA hydrogel for regenerating periodontal bone defects

Guangna Yue, Cheng Cheng, Lu Qiang
Frontiers in Bioengineering and Biotechnology
Graphene and Nanomaterials Applications
article

Synergistic antibacterial and osteogenic activities of GO/GelMA hydrogel for regenerating periodontal bone defects

Guangna Yue, Cheng Cheng, Lu Qiang
article en

Abstract

Objective: experiments. Methods: validation. Results: results revealed that the 200 µg/mL GO/GelMA group achieved the most significant alveolar bone regeneration and the lowest levels of inflammatory factors. Conclusion: The GO/GelMA hydrogels, particularly at a GO concentration of 200 µg/mL, demonstrate excellent synergistic antibacterial and osteogenic properties, holding great promise for treating periodontitis-related bone defects.

Frontiers in Bioengineering and BiotechnologyVol. 14
Beijing University of Chinese Medicine (CN), Shanghai East Hospital (CN)
Openalex Percentile: Top 23%
Graphene and Nanomaterials Applications
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