The multiple positive effects of Honghua Ruyi Pills combined with estradiol valerate and dydrogesterone tablets on postoperative recovery in women after artificial abortion

Objectives: To evaluate the efficacy of Honghua Ruyi Pills combined with estradiol valerate and dydrogesterone tablets in promoting endometrial repair and menstrual recovery after artificial abortion. Methods: = 133). The primary outcome was endometrial thickness at 1 week post-surgery. Secondary outcomes included time to postoperative abdominal pain resolution, postoperative vaginal bleeding duration, time to menstruation resumption, postoperative menstrual duration, menstrual volume, menstrual blood color, and the incidence of adverse reactions. All outcomes were assessed after a 21-day treatment period. Results: < 0.001). The incidence of adverse reactions did not differ significantly among the three groups. Conclusion: In this single-center trial, the combination of Honghua Ruyi Pills with estradiol valerate and dydrogesterone tablets showed preliminary superiority in promoting short-term endometrial repair and menstrual recovery after artificial abortion compared with either treatment alone. These findings are hypothesis-generating and warrant confirmation in multicenter trials with longer follow-up and clinically relevant reproductive endpoints such as pregnancy rate and intrauterine adhesion formation.