A Case of Spontaneous Umbilical Endometriosis

Umbilical endometriosis, also known as Villar’s nodule, is an atypical manifestation of endometriosis. We present a rare case of spontaneous Villar’s nodule in a young, nulliparous woman with no history of abdominal surgery or trauma who had no classic symptoms of endometriosis. Clinical examination revealed a painless umbilical nodule, and histopathologic evaluation demonstrated endometrial-type glands and stroma, confirming primary cutaneous endometriosis. Further gynecologic evaluation, including pelvic examination and transvaginal ultrasound, showed no evidence of pelvic endometriosis. We review proposed pathogenic mechanisms, discuss diagnostic considerations, and highlight the importance of prompt gynecologic referral. Early recognition with complete excision and appropriate gynecologic follow-up is essential, particularly in patients desiring future fertility.

Authors

Publication Details

Journal
Cureus
Published
2026-04-22
DOI
https://doi.org/10.7759/cureus.107516
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case of Spontaneous Umbilical Endometriosis

Jennifer J Law, Victoria C Kuritza
Cureus
Endometriosis Research and Treatment
article

A Case of Spontaneous Umbilical Endometriosis

Jennifer J Law, Victoria C Kuritza
article en

Abstract

Umbilical endometriosis, also known as Villar’s nodule, is an atypical manifestation of endometriosis. We present a rare case of spontaneous Villar’s nodule in a young, nulliparous woman with no history of abdominal surgery or trauma who had no classic symptoms of endometriosis. Clinical examination revealed a painless umbilical nodule, and histopathologic evaluation demonstrated endometrial-type glands and stroma, confirming primary cutaneous endometriosis. Further gynecologic evaluation, including pelvic examination and transvaginal ultrasound, showed no evidence of pelvic endometriosis. We review proposed pathogenic mechanisms, discuss diagnostic considerations, and highlight the importance of prompt gynecologic referral. Early recognition with complete excision and appropriate gynecologic follow-up is essential, particularly in patients desiring future fertility.

Cureus
Good health and well-being
Openalex Percentile: Top 6%
Endometriosis Research and Treatment
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