Case Report: Antenatal diagnosis of double-chambered right ventricle in two cases: follow-up and literature review

Double-chambered right ventricle (DCRV) is defined as the progressive division of the right ventricle into two chambers: a high-pressure inlet chamber and a low-pressure outlet chamber. To date, only three cases diagnosed prenatally have been reported in the literature, all of which were associated with unfavorable pregnancy outcomes. In this study, we discuss DCRV in general, along with two cases of type 1 DCRV that did not cause hemodynamically significant obstruction and resulted in successful pregnancy outcomes. From a hemodynamic perspective, the following echocardiographic criteria may affect the prenatal fetal process: (1) detection of tricuspid regurgitation on echocardiography; and (2) pulmonary blood flow velocity and the difference in pressure between the proximal and distal right ventricle.

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Journal
Frontiers in Cardiovascular Medicine
Published
2026-04-22
DOI
https://doi.org/10.3389/fcvm.2026.1760854
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Case Report: Antenatal diagnosis of double-chambered right ventricle in two cases: follow-up and literature review

Kazım Öztarhan, Ali Gedikbaşı, Selda Atar, Aylin Oztarhan et al.
Frontiers in Cardiovascular Medicine
Congenital Heart Disease Studies
article

Case Report: Antenatal diagnosis of double-chambered right ventricle in two cases: follow-up and literature review

Kazım Öztarhan, Ali Gedikbaşı, Selda Atar, Aylin Oztarhan, İdil Kaçur, Aysin Kale
article en

Abstract

Double-chambered right ventricle (DCRV) is defined as the progressive division of the right ventricle into two chambers: a high-pressure inlet chamber and a low-pressure outlet chamber. To date, only three cases diagnosed prenatally have been reported in the literature, all of which were associated with unfavorable pregnancy outcomes. In this study, we discuss DCRV in general, along with two cases of type 1 DCRV that did not cause hemodynamically significant obstruction and resulted in successful pregnancy outcomes. From a hemodynamic perspective, the following echocardiographic criteria may affect the prenatal fetal process: (1) detection of tricuspid regurgitation on echocardiography; and (2) pulmonary blood flow velocity and the difference in pressure between the proximal and distal right ventricle.

Frontiers in Cardiovascular MedicineVol. 13
Acıbadem University (TR), Memorial Sisli Hospital (TR), Precision for Medicine (United States) (US), Sağlık Bilimleri Üniversitesi (TR), Şişli Etfal Eğitim ve Araştırma Hastanesi (TR), Acıbadem Adana Hospital (TR), Istanbul University (TR)
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Openalex Percentile: Top 22%
Congenital Heart Disease Studies
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