Rosai–Dorfman disease presenting as isolated cervical lymphadenopathy in a young adult: A case report

, in a significant subset of cases, supporting a clonal neoplastic component. The clinical course of cervical RDD is generally favorable, and management is individualized, ranging from observation to surgical excision in cases of compressive symptoms, with systemic or targeted therapies reserved for refractory or multisystem disease. We report the case of a 25-year-old patient with no significant past medical history who presented with a persistent cervical lymphadenopathy. Comprehensive clinical evaluation, laboratory investigations, and imaging studies supported the diagnosis of Rosai-Dorfman disease. Prompt recognition and appropriate surgical management play a crucial role in achieving favorable clinical outcomes.