Intraprocedural atrial tachycardia during ablation of paroxysmal atrial fibrillation: incidence, mechanisms, and clinical outcomes
Background: Radiofrequency catheter ablation (RFCA) is the mainstay treatment for paroxysmal atrial fibrillation (PAF). However, the incidence, risk factors, and impact of intra-procedural atrial tachycardia (IAT) during PAF ablation remain insufficiently characterized. The purpose of this study was to explore the incidence, risk factors, electrophysiological features, and clinical outcomes of IAT. Methods: In this single-center, prospective study, 255 patients undergoing RFCA for PAF were analyzed. IAT was defined as stable tachycardia lasting more than 2 min, either induced or spontaneous. Logistic regression identified risk factors for AT, and Kaplan-Meier analysis was used to examine its impact on long-term success. Results: = 0.84). Conclusions: IAT was observed in 13.3% of patients undergoing PAF ablation, with macro-reentrant circuits around the tricuspid and mitral annuli being the primary mechanisms. Right atrial diameter served as a key predictor. Our data demonstrate that with successful intra-procedural identification and targeted ablation, IAT patients can achieve a 12-month prognosis similar to non-IAT patients.
Authors
- F Zhang
- Q Chen
- Zhongda Chen (ORCID: https://orcid.org/0000-0003-0518-7938)
- Yan Dong (ORCID: https://orcid.org/0000-0003-2654-5191)
- Yuan He (ORCID: https://orcid.org/0000-0003-3086-4371)
- Nishant Yadav
- Youfu Huang (ORCID: https://orcid.org/0000-0002-0809-1897)
- Wei Zhao
- Li Jiang
- Xuesheng Fan
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-04-22
- DOI
- https://doi.org/10.3389/fcvm.2026.1822766
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00