Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

approach, which offer valuable insights into the interactions of NF with various biological targets. However, despite its therapeutic potential, several challenges remain in translating the use of NF into clinical applications. These include concerns regarding its toxicity or undesirable effects, as well as issues associated with its bioavailability and drug delivery profile. Future research should focus on addressing these challenges to fully realize the therapeutic potential of NF across a range of diseases.