Tyloxapol inhibits ESX-1 secretion in <i>Mycobacterium marinum</i>
infection of both animals and macrophages. Our study also indicates that tyloxapol can be used as a tool to understand the molecular mechanisms of ESX-1 protein secretion.
Authors
- Simon D. Weaver (ORCID: https://orcid.org/0000-0003-4354-0309)
- Owen A. Collars (ORCID: https://orcid.org/0009-0002-1736-5770)
- Matthew M. Champion (ORCID: https://orcid.org/0000-0001-5927-5277)
- Patricia A. Champion (ORCID: https://orcid.org/0000-0002-6733-596X)
- Richard L Hernandez
Institutions
- University of Notre Dame (US)
Publication Details
- Journal
- Journal of Bacteriology
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1128/jb.00136-26
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 21.24