Trigger Factor in <i>Burkholderia pseudomallei</i> is essential for key virulence determinants, including host cell internalization, cytotoxicity, motility, and stress resistance
and is a potential target for anti-virulence therapy. IMPORTANCE: virulence factor that can be potentially exploited for the development of new therapeutics to treat this deadly infection.
Authors
- Mitali Sarkar‐Tyson (ORCID: https://orcid.org/0000-0002-6764-8499)
- Aleksandra W. Debowski (ORCID: https://orcid.org/0000-0002-9105-3989)
- Nichollas E. Scott (ORCID: https://orcid.org/0000-0003-2556-8316)
- Jua Iwasaki (ORCID: https://orcid.org/0000-0002-5833-7146)
- Nicole M. Bzdyl (ORCID: https://orcid.org/0000-0003-2204-1172)
- Charles S. Bond (ORCID: https://orcid.org/0000-0002-9584-6783)
- Keith A. Stubbs (ORCID: https://orcid.org/0000-0001-6899-402X)
- Justine Bendo (ORCID: https://orcid.org/0000-0002-8278-0076)
- Josephine Starr
Institutions
- The University of Melbourne (AU)
- The Kids Research Institute Australia (AU)
- The University of Western Australia (AU)
- Peter Doherty Institute (AU)
- Centre for Clinical Interventions (AU)
- ARC Centre of Excellence in Advanced Molecular Imaging (AU)
Publication Details
- Journal
- Journal of Bacteriology
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1128/jb.00124-26
- Primary Topic
- Burkholderia infections and melioidosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- DMTC