PTEN: Regulation, Signalling and Targeting in Cancer

PTEN (phosphatase and tensin homolog deleted on chromosome ten)/MMAC1 (mutated in multiple advanced cancers) was discovered by two groups in 1997 as a novel tumor suppressor gene located at chromosome 10q23 [...]

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Publication Details

Journal
Cancers
Published
2026-04-22
DOI
https://doi.org/10.3390/cancers18091320
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

PTEN: Regulation, Signalling and Targeting in Cancer

Larissa Kotelevets, Eric Chastre, Mark G. H. Scott
Cancers
PI3K/AKT/mTOR signaling in cancer
article

PTEN: Regulation, Signalling and Targeting in Cancer

Larissa Kotelevets, Eric Chastre, Mark G. H. Scott
article en

Abstract

PTEN (phosphatase and tensin homolog deleted on chromosome ten)/MMAC1 (mutated in multiple advanced cancers) was discovered by two groups in 1997 as a novel tumor suppressor gene located at chromosome 10q23 [...]

CancersVol. 18(9)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris Cité (FR), Sorbonne Université (FR), Centre de Recherche Saint-Antoine (FR), Institut Cochin (FR)
Fondation ARC pour la Recherche sur le Cancer, Ligue Contre le Cancer
Good health and well-being
Openalex Percentile: Top 8%
PI3K/AKT/mTOR signaling in cancer
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