Complete symptomatic resolution following surgical resection of a spinal tanycytic ependymoma: a case report

BACKGROUND: Tanycytic ependymoma (TCE) is a rare grade II ependymoma primarily located in the spinal cord, arising from tanycytes. The average age of onset is 34.5 years. Definitive diagnosis is achieved through histological analysis. This case report highlights the complete symptomatic resolution following successful surgical intervention in a patient with a rare spinal TCE. It underscores the importance of early diagnosis and treatment, as timely intervention can significantly enhance a patient's chance for full recovery. CASE PRESENTATION: A 23-year-old Syrian woman with a year of worsening lower back pain and mild paresthesias was diagnosed with a TCE after magnetic resonance imaging (MRI) revealed an intramedullary mass at T10-T11. Surgical resection was successfully performed with care to minimize bleeding. Histological analysis confirmed the tumor type through spindle cell morphology and GFAP positivity. The patient achieved full recovery 6 months post-surgery. CONCLUSION: Due to nonspecific radiological features of TCE, timely diagnosis requires thorough neurological evaluation, and early referral to specialized centers is advised for suspected cases, as prompt surgical resection can enhance outcomes.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-04-22
DOI
https://doi.org/10.1186/s13256-026-06054-3
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

Complete symptomatic resolution following surgical resection of a spinal tanycytic ependymoma: a case report

Wardan Almir Tamer, Mulham Alkassem, Saja Karaja, William Borghol et al.
Journal of Medical Case Reports
Glioma Diagnosis and Treatment
article

Complete symptomatic resolution following surgical resection of a spinal tanycytic ependymoma: a case report

Wardan Almir Tamer, Mulham Alkassem, Saja Karaja, William Borghol, Habib Jarbouh, Khayry Al-Shami
article en

Abstract

BACKGROUND: Tanycytic ependymoma (TCE) is a rare grade II ependymoma primarily located in the spinal cord, arising from tanycytes. The average age of onset is 34.5 years. Definitive diagnosis is achieved through histological analysis. This case report highlights the complete symptomatic resolution following successful surgical intervention in a patient with a rare spinal TCE. It underscores the importance of early diagnosis and treatment, as timely intervention can significantly enhance a patient's chance for full recovery. CASE PRESENTATION: A 23-year-old Syrian woman with a year of worsening lower back pain and mild paresthesias was diagnosed with a TCE after magnetic resonance imaging (MRI) revealed an intramedullary mass at T10-T11. Surgical resection was successfully performed with care to minimize bleeding. Histological analysis confirmed the tumor type through spindle cell morphology and GFAP positivity. The patient achieved full recovery 6 months post-surgery. CONCLUSION: Due to nonspecific radiological features of TCE, timely diagnosis requires thorough neurological evaluation, and early referral to specialized centers is advised for suspected cases, as prompt surgical resection can enhance outcomes.

Journal of Medical Case Reports
Häme University of Applied Sciences (FI), Universitas Muhammadiyah Prof Dr Hamka (ID), Yarmouk University (JO), Damascus University (SY)
Good health and well-being
Openalex Percentile: Top 8%
Glioma Diagnosis and Treatment
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